B Cell Receptor Signaling. Tomohiro Kurosaki

B Cell Receptor Signaling


B.Cell.Receptor.Signaling.pdf
ISBN: 9783319261317 | 231 pages | 6 Mb


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B Cell Receptor Signaling Tomohiro Kurosaki
Publisher: Springer International Publishing



B cell receptor signaling pathway - Homo sapiens (human), Help. Doi: 10.1182/blood-2014-03-559690. B cell receptor signaling and autoimmunity. The outcome of B-cell receptor signaling in chronic lymphocytic leukemia: proliferation or anergy. The B-cell receptor signaling pathway as a therapeutic target in CLL. Basal B-cell receptor signaling in B lymphocytes: mechanisms of regulation and role in positive selection, differentiation, and peripheral survival. The functional B-cell receptor is a multi-protein complex consisting of an antigen binding subunit and a signaling subunit. Phosphoproteomic analyses reveal that galectin-1 augments the dynamics of B-cell receptor signaling. Model for signaling via the B cell receptor. CD22 ligation inhibits downstream B cell receptor signaling and Ca(2+) flux upon activation. The membrane Ig (depicted in black) inserts into the cell membrane via its Fc portion. Hematology Am Soc Hematol Educ Program. Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma. Doi: 10.1182/ asheducation-2013.1.553. Doi: 10.3109/10428194.2013.796055. The majority of early immature B cells express autoreactive B cell receptors ( BCRs) Pre-B Cell Receptor Signaling and Induce Proliferation of Early B Cells.





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